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Rabbit anti-Human PLCB2 Polyclonal Antibody

The antibody against PLCB2 was raised in rabbit using the Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-54971A

The antibody against PLCB2 was raised in rabbit using the Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-54971A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePLCB2
Target Synonyms1 phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2), PLCB2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 protein (1031-1185aa)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ00722
Background Information
  • Uniprot Id

    Q00722

  • Target Species

    Human

  • Target Name

    PLCB2

  • Target Full Name

    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

  • Target Function

    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

  • Target Synonyms

    PLC-beta-2; PLCB2

  • Target Background

    The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to the second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

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