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The antibody against PLCH1 was raised in rabbit using the Human PLCH1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PLCH1 was raised in rabbit using the Human PLCH1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-52338A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLCH1 |
| Target Synonyms | 1-phosphatidylinositol 4 antibody; 1-phosphatidylinositol-4 antibody; 1-phosphatidylinositol-4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PLCH1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q4KWH8 |
Uniprot Id
Q4KWH8
Target Species
Human
Target Name
PLCH1
Target Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
Target Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.
Target Subcellular Location
Cytoplasm. Membrane.
Target Tissue Specificity
Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord.
Target Synonyms
1-phosphatidylinositol 4; 1-phosphatidylinositol-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1; 5-bisphosphate phosphodiesterase eta-1; DKFZp434C1372; KIAA1069; MGC117152; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; Phospholipase C-like protein 3; PLC-eta-1; PLC-L3; PLCeta1; Plch1; PLCH1_HUMAN; PLCL3
Target Background
PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4, 5-bisphosphate (PtdIns(4, 5)P2) to generate second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).
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