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Rabbit anti-Human PLEKHA3 Polyclonal Antibody

The antibody against PLEKHA3 was raised in rabbit using the Human PLEKHA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47605A

The antibody against PLEKHA3 was raised in rabbit using the Human PLEKHA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47605A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePLEKHA3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PLEKHA3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9HB20
Background Information
  • Uniprot Id

    Q9HB20

  • Target Species

    Human

  • Target Name

    PLEKHA3

  • Target Full Name

    Pleckstrin homology domain-containing family A member 3

  • Target Function

    Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane. Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration. Binds preferentially to PtdIns(4)P. Negatively regulates APOB secretion from hepatocytes.

  • Target Subcellular Location

    Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    PLEKHA3; FAPP1; Pleckstrin homology domain-containing family A member 3; PH domain-containing family A member 3; Phosphatidylinositol-four-phosphate adapter protein 1; FAPP-1; Phosphoinositol 4-phosphate adapter protein 1

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