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The antibody against PLEKHA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLEKHA7 (NP_778228.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against PLEKHA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLEKHA7 (NP_778228.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-07314A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLEKHA7 |
| Target Synonyms | PLEKHA7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLEKHA7 (NP_778228.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6IQ23 | Immunogen Sequence |
Uniprot Id
Q6IQ23
Target Species
Human
Target Name
PLEKHA7
Target Full Name
Pleckstrin homology domain-containing family A member 7
Target Function
Required for zonula adherens biogenesis and maintenance. Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site. Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33.
Target Subcellular Location
Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Synonyms
DKFZp686M22243; PH domain-containing family A member 7; PKHA7_HUMAN; Pleckstrin homology domain containing family A member 2; Pleckstrin homology domain-containing family A member 7; Plekha7
Target Background
Enables delta-catenin binding activity. Involved in epithelial cell-cell adhesion; pore complex assembly; and zonula adherens maintenance. Located in several cellular components, including centrosome; nucleoplasm; and zonula adherens. Part of pore complex.
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