Rabbit anti-Human Plexin A1 Monoclonal Antibody

The antibody against Plexin A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human Plexin A1 (Q9UIW2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-16195A

Number

Cat.No	ADA-16195A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Plexin A1
Target Synonyms	NOV; NOVP; PLXN1; DWOPNED; PLEXIN-A1; Plexin A1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	K-562, Mouse brain, Rat testis	Application	ELISA, WB

Cat.No

ADA-16195A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Plexin A1

Target Synonyms

NOV; NOVP; PLXN1; DWOPNED; PLEXIN-A1; Plexin A1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

K-562, Mouse brain, Rat testis

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Plexin A1 (Q9UIW2).	Target Species	Human
Immunogen Sequence	SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPT	Uniprot ID	Q9UIW2

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Plexin A1 (Q9UIW2).

Target Species

Human

Immunogen Sequence

SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPT

Uniprot ID

Q9UIW2

Background Information

Uniprot Id

Q9UIW2
Target Species

Human
Target Name

PLXNA1
Target Full Name

Plexin-A1
Target Function

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

Plexin family
Target Tissue Specificity

Detected in fetal brain, lung, liver and kidney.
Target Research Area

Neuroscience
Target Synonyms

PLXNA1; NOV; PLXN1; Plexin-A1; Semaphorin receptor NOV
Target Background

Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including generation of neurons; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within dichotomous subdivision of terminal units involved in salivary gland branching; neuron projection morphogenesis; and regulation of smooth muscle cell migration. Located in cytosol and nucleoplasm.

Rabbit anti-Human Plexin A1 Monoclonal Antibody

Specifications

Immunogen Information

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