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The antibody against PLS1 was raised in rabbit using the Recombinant Human Plastin-1 protein (1-143AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PLS1 was raised in rabbit using the Recombinant Human Plastin-1 protein (1-143AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04090A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLS1 |
| Target Synonyms | PLS1 antibody; Plastin-1 antibody; Intestine-specific plastin antibody; I-plastin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Plastin-1 protein (1-143AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14651 |
Uniprot Id
Q14651
Target Species
Human
Target Name
PLS1
Target Full Name
Plastin-1
Target Function
Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
Target Subcellular Location
Cytoplasm. Cell projection, stereocilium.
Target Tissue Specificity
In small intestine, colon, and kidney; relatively lower levels of expression are detected in the lung and stomach.
Target Synonyms
PLS1; Plastin-1; Intestine-specific plastin; I-plastin
Target Background
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.
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