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The antibody against PLXDC1 was raised in rabbit using the Synthesized peptide derived from Internal of Human PLXDC1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
The antibody against PLXDC1 was raised in rabbit using the Synthesized peptide derived from Internal of Human PLXDC1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using PLXDC1 antibody.
| Cat.No | ADC-41901A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLXDC1 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Internal of Human PLXDC1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IUK5 |
Uniprot Id
Q8IUK5
Target Species
Human
Target Name
PLXDC1
Target Full Name
Plexin domain-containing protein 1
Target Function
Plays a critical role in endothelial cell capillary morphogenesis.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.
Target Protein Families
Plexin family
Target Tissue Specificity
Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased
Target Research Area
Cardiovascular
Target Synonyms
DKFZp686F0937 ; FLJ36270; FLJ45632; OTTHUMP00000164240; Plexin domain containing 1; Plexin domain containing protein 1 precursor; Plexin domain-containing protein 1; Plxdc1; PXDC1_HUMAN; TEM3; TEM7; Tumor endothelial marker 3; Tumor endothelial marker 7
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