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The antibody against PLXNB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-470 of human PLXNB1 (NP_002664.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PLXNB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-470 of human PLXNB1 (NP_002664.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01181A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLXNB1 |
| Target Synonyms | SEP; PLXN5; PLEXIN-B1; PLXNB1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | LO2, Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 250-470 of human PLXNB1 (NP_002664.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43157 | Immunogen Sequence |
Uniprot Id
O43157
Target Species
Human
Target Name
PLXNB1
Target Full Name
Plexin-B1
Target Function
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Target Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.
Target Protein Families
Plexin family
Target Tissue Specificity
Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.
Target Research Area
Neuroscience
Target Synonyms
PLXNB1; KIAA0407; PLXN5; SEP; Plexin-B1; Semaphorin receptor SEP
Target Background
Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Is integral component of plasma membrane. Part of semaphorin receptor complex.
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