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The antibody against PMCH was raised in rabbit using the Synthetic peptide from Human protein at AA range: 112-161 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against PMCH was raised in rabbit using the Synthetic peptide from Human protein at AA range: 112-161 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
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Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:2002
| Cat.No | ADC-12965A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PMCH |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 112-161 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20382 |
Uniprot Id
P20382
Target Species
Human
Target Name
PMCH
Target Full Name
Pro-MCH
Target Function
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
Target Subcellular Location
Secreted.
Target Protein Families
Melanin-concentrating hormone family
Target Tissue Specificity
Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood
Target Synonyms
PMCH; MCHPro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid; NGE; Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine; NEI; Neuropeptide E-I); Melanin-concentrating hormone; MCH)]
Target Background
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of this gene have been identified on chromosome 5.
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