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The antibody against PNLDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PNLDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNLDC1 |
| Target Synonyms | SPGF57; Trimmer; HsPNLDC1; PNLDC1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain, Mouse liver, Mouse testis, Raji, Rat testis, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8NA58 | Immunogen Sequence |
Uniprot Id
Q8NA58
Target Species
Human
Target Name
PNLDC1
Target Full Name
Poly(A)-specific ribonuclease PNLDC1
Target Function
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
CAF1 family
Target Synonyms
oly(A)-specific ribonuclease PARN-like domain-containing protein 1; PNDC1_HUMAN; PNLDC1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease PARN-like domain-containing protein 1; RP1-195P10.1
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