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The antibody against PNMA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human PNMA1 (NP_006020.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PNMA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human PNMA1 (NP_006020.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05572A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNMA1 |
| Target Synonyms | MA1; PNMA1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T, Mouse testis, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human PNMA1 (NP_006020.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8ND90 | Immunogen Sequence |
Uniprot Id
Q8ND90
Target Species
Human
Target Name
PNMA1
Target Full Name
Paraneoplastic antigen Ma1
Target Subcellular Location
Nucleus, nucleolus. Note=In tumor cells, it is cytoplasmic.
Target Protein Families
PNMA family
Target Tissue Specificity
Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells.
Target Research Area
others
Target Synonyms
37 kDa neuronal protein; MA1; Neuron- and testis-specific protein 1; Paraneoplastic antigen Ma1; paraneoplastic neuronal antigen MA1; Pnma1; PNMA1_HUMAN
Target Background
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors.
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