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The antibody against PNMA1 was raised in rabbit using the Recombinant Human Paraneoplastic antigen Ma1 protein (151-353AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against PNMA1 was raised in rabbit using the Recombinant Human Paraneoplastic antigen Ma1 protein (151-353AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-24045A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNMA1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Paraneoplastic antigen Ma1 protein (151-353AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8ND90 |
Uniprot Id
Q8ND90
Target Species
Human
Target Name
PNMA1
Target Full Name
Paraneoplastic antigen Ma1
Target Subcellular Location
Nucleus, nucleolus. Note=In tumor cells, it is cytoplasmic.
Target Protein Families
PNMA family
Target Tissue Specificity
Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells.
Target Research Area
others
Target Synonyms
37 kDa neuronal protein; MA1; Neuron- and testis-specific protein 1; Paraneoplastic antigen Ma1; paraneoplastic neuronal antigen MA1; Pnma1; PNMA1_HUMAN
Target Background
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors.
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