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The antibody against PNO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human PNO1 (NP_064528.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PNO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human PNO1 (NP_064528.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07060A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNO1 |
| Target Synonyms | RRP20; KHRBP1; PNO1 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, LO2, MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human PNO1 (NP_064528.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NRX1 | Immunogen Sequence |
Uniprot Id
Q9NRX1
Target Species
Human
Target Name
PNO1
Target Full Name
RNA-binding protein PNO1
Target Function
Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
PNO1 family
Target Tissue Specificity
Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary. Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon and peripheral blood leukocytes.
Target Research Area
Cancer
Target Synonyms
PNO1; RNA-binding protein PNO1
Target Background
Enables RNA binding activity. Located in nucleolus and nucleoplasm.
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