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The antibody against PNPLA6 was raised in rabbit using the Synthesized peptide derived from internal of Human PNPLA6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against PNPLA6 was raised in rabbit using the Synthesized peptide derived from internal of Human PNPLA6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from COLO205 cells, using PNPLA6 antibody.
| Cat.No | ADC-41077A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNPLA6 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PNPLA6. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IY17 |
Uniprot Id
Q8IY17
Target Species
Human
Target Name
PNPLA6
Target Full Name
Patatin-like phospholipase domain-containing protein 6
Target Function
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides.
Target Involvement
Spastic paraplegia 39, autosomal recessive (SPG39); Boucher-Neuhauser syndrome (BNHS); Laurence-Moon syndrome (LNMS); Oliver-McFarlane syndrome (OMCS)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Target Protein Families
NTE family
Target Tissue Specificity
Expressed in brain, placenta, kidney, neuron and skeletal muscle. Expressed in the developing eye, pituitary and brain.
Target Synonyms
EC 3.1.1.5; Neuropathy target esterase; NTEMND; Patatin like phospholipase domain containing 6; Patatin like phospholipase domain containing protein 6; Patatin-like phospholipase domain-containing protein 6; PLPL6_HUMAN; Pnpla6; SPG39; sws
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