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The antibody against POLR1E was raised in rabbit using the Synthesized peptide derived from the Internal region of Human POLR1E. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against POLR1E was raised in rabbit using the Synthesized peptide derived from the Internal region of Human POLR1E. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-34132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POLR1E |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human POLR1E. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZS1 |
Uniprot Id
Q9GZS1
Target Species
Human
Target Name
POLR1E
Target Full Name
DNA-directed RNA polymerase I subunit RPA49
Target Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
Eukaryotic RPA49/POLR1E RNA polymerase subunit family
Target Synonyms
A49; DNA directed RNA polymerase I subunit RPA49; DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ 13390; FLJ13970; PAF53; POLR 1 E; POLR1E; Polymerase (RNA) I associated factor 1; Polymerase (RNA) I polypeptide E; Polymerase (RNA) I polypeptide E, 53kDa; PRAF1; RNA polymerase I associated factor 1; RNA polymerase I associated factor 53; RNA polymerase I polypeptide E; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11405L18.3; RPA49_HUMAN
Target Background
Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and RNA polymerase I general transcription initiation factor binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in fibrillar center and nucleoplasm.
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