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Rabbit anti-Human POLR2H Polyclonal Antibody

The antibody against POLR2H was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human POLR2H (NP_006223.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-03590A

The antibody against POLR2H was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human POLR2H (NP_006223.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

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Specifications


Cat.No ADA-03590A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePOLR2H
Target SynonymsRPB8; RPB17; RPABC3; POLR2HFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293T, HL-60, MCF7, Mouse spleen, Mouse thymus, SW480ApplicationELISA, WB, IP

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human POLR2H (NP_006223.2).Target SpeciesHuman
Immunogen SequenceMAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVIASTLYEDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGGLLMRLQGDANNLHGFEVDSRVYLLMKKLAFUniprot IDP52434
Background Information
  • Uniprot Id

    P52434

  • Target Species

    Human

  • Target Name

    POLR2H

  • Target Full Name

    DNA-directed RNA polymerases I, II, and III subunit RPABC3

  • Target Function

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Protein Families

    Eukaryotic RPB8 RNA polymerase subunit family

  • Target Synonyms

    POLR2H; DNA-directed RNA polymerases I; II; and III subunit RPABC3; RNA polymerases I; II; and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I; II; and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8

  • Target Background

    The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene.

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