Rabbit anti-Human POU1F1 Polyclonal Antibody

The antibody against POU1F1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 124-273 of human POU1F1 (NP_000297.1?) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07180A

Number

Cat.No	ADA-07180A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	POU1F1
Target Synonyms	PIT1; CPHD1; GHF-1; Pit-1; POU1F1a; POU1F1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T transfected with POU1F1	Application	ELISA, WB

Cat.No

ADA-07180A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

POU1F1

Target Synonyms

PIT1; CPHD1; GHF-1; Pit-1; POU1F1a; POU1F1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T transfected with POU1F1

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 124-273 of human POU1F1 (NP_000297.1?).	Target Species	Human
Immunogen Sequence	MDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK	Uniprot ID	P28069

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 124-273 of human POU1F1 (NP_000297.1?).

Target Species

Human

Immunogen Sequence

MDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK

Uniprot ID

P28069

Background Information

Uniprot Id

P28069
Target Species

Human
Target Name

POU1F1
Target Full Name

Pituitary-specific positive transcription factor 1
Target Function

Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes.
Target Involvement

Pituitary hormone deficiency, combined, 1 (CPHD1)
Target Subcellular Location

Nucleus.
Target Protein Families

POU transcription factor family, Class-1 subfamily
Target Synonyms

Dwarf; GHF 1; GHF 1A; GHF-1; GHF1; GHF1A; Growth hormone factor 1; Hmp 1; Hmp1; Pit 1; Pit 1 beta; PIT 1Z; PiT-1; Pit1 beta; PIT1_HUMAN; PIT1Z; Pituitary growth hormone; Pituitary specific positive transcription factor 1; Pituitary-specific positive transcription factor 1; POU class 1 homeobox 1; POU domain class 1 transcription factor 1; POU domain transcriptional regulator; POU1F1
Target Background

This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human POU1F1 Polyclonal Antibody

Specifications

Immunogen Information

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