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The antibody against PPA2 was raised in rabbit using the Recombinant Human Inorganic pyrophosphatase 2, mitochondrial protein (180-298AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against PPA2 was raised in rabbit using the Recombinant Human Inorganic pyrophosphatase 2, mitochondrial protein (180-298AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-04641A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPA2 |
| Target Synonyms | HSPC124 antibody; Inorganic pyrophosphatase 2 antibody; Inorganic pyrophosphatase 2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Inorganic pyrophosphatase 2, mitochondrial protein (180-298AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2U2 |
Uniprot Id
Q9H2U2
Target Species
Human
Target Name
PPA2
Target Full Name
Inorganic pyrophosphatase 2, mitochondrial
Target Function
Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function.
Target Involvement
Sudden cardiac failure, alcohol-induced (SCFAI); Sudden cardiac failure, infantile (SCFI)
Target Subcellular Location
Mitochondrion.
Target Protein Families
PPase family
Target Tissue Specificity
Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
Target Synonyms
HSPC124; Inorganic pyrophosphatase 2; Inorganic pyrophosphatase 2, mitochondrial; IPYR2_HUMAN; mitochondrial; Ppa2; PPase 2; PPase2; Pyrophosphatase (inorganic) 2; Pyrophosphatase SID6 306 ; Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; SID6 306
Target Background
The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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