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The antibody against PPM1G was raised in rabbit using the Human PPM1G as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PPM1G was raised in rabbit using the Human PPM1G as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-52274A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPM1G |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human PPM1G | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15355 |
Uniprot Id
O15355
Target Species
Human
Target Name
PPM1G
Target Full Name
Protein phosphatase 1G
Target Subcellular Location
Cytoplasm. Membrane; Lipid-anchor.
Target Protein Families
PP2C family
Target Tissue Specificity
Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Target Synonyms
MGC1675; MGC2870; OTTHUMP00000123426; PP2C; PP2C gamma; PP2C-gamma; PP2CG; PP2Cgamma; PPM1G; PPM1G_HUMAN; PPP2CG; Protein phosphatase 1C; Protein phosphatase 1G; Protein phosphatase 2 catalytic subunit gamma isoform; Protein phosphatase 2C gamma isoform ; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium dependent 1 gamma; Protein phosphatase magnesium-dependent 1 gamma; Protein phosphatase Mg2+/Mn2+ dependent 1G
Target Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
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