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The antibody against PPME1 was raised in rabbit using the Recombinant Human Protein phosphatase methylesterase 1 protein (201-386AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PPME1 was raised in rabbit using the Recombinant Human Protein phosphatase methylesterase 1 protein (201-386AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-32861A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPME1 |
| Target Synonyms | PME 1 antibody; PME-1 antibody; PME1 antibody; PPME1 antibody; PPME1_HUMAN antibody; Protein phosphatase methylesterase 1 antibody; Testicular Secretory Protein Li 39 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein phosphatase methylesterase 1 protein (201-386AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y570 |
Uniprot Id
Q9Y570
Target Species
Human
Target Name
PPME1
Target Full Name
Protein phosphatase methylesterase 1
Target Function
Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.
Target Protein Families
AB hydrolase superfamily
Target Synonyms
PME 1; PME-1; PME1; PPME1; PPME1_HUMAN; Protein phosphatase methylesterase 1; Testicular Secretory Protein Li 39
Target Background
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.
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