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Rabbit anti-Human PPP1R13L Polyclonal Antibody

The antibody against PPP1R13L was raised in rabbit using the Synthetic peptide of Human PPP1R13L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-28290A

The antibody against PPP1R13L was raised in rabbit using the Synthetic peptide of Human PPP1R13L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-28290A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePPP1R13L
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human PPP1R13LTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WUF5
Background Information
  • Uniprot Id

    Q8WUF5

  • Target Species

    Human

  • Target Name

    PPP1R13L

  • Target Full Name

    RelA-associated inhibitor

  • Target Function

    Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    ASPP family

  • Target Tissue Specificity

    Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.

  • Target Synonyms

    PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI; RelA-associated inhibitor; Inhibitor of ASPP protein; Protein iASPP; NFkB-interacting protein 1; PPP1R13B-like protein

  • Target Background

    IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.

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