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The antibody against PPP1R3C was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PTG. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against PPP1R3C was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PTG. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-34586A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP1R3C |
| Target Synonyms | OTTHUMP00000020089 antibody; Phosphatase 1, regulatory (inhibitor) subunit 3C antibody; Protein targeting to glycogen antibody; PTG antibody; R5 antibody | Form | Liquid |
| Species Reactivity | Human, Monkey | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human PTG. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UQK1 |
Uniprot Id
Q9UQK1
Target Species
Human
Target Name
PPP1R3C
Target Full Name
Protein phosphatase 1 regulatory subunit 3C
Target Function
Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
Target Synonyms
OTTHUMP00000020089; Phosphatase 1, regulatory inhibitor subunit 5; PP1 subunit R5; ppp1r3c; PPP1R5; PPR3C_HUMAN; Protein phosphatase 1 inhibitor 3C; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; Protein targeting to glycogen; PTG; R5
Target Background
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
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