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The antibody against PPP2R1B was raised in rabbit using the Synthesized peptide derived from internal of Human PPP2R1B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against PPP2R1B was raised in rabbit using the Synthesized peptide derived from internal of Human PPP2R1B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from Jurkat cells and HeLa cells, using PPP2R1B antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PPP2R1B antibody.2
| Cat.No | ADC-40923A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP2R1B |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PPP2R1B. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P30154 |
Uniprot Id
P30154
Target Species
Human
Target Name
PPP2R1B
Target Full Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Target Function
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
Target Protein Families
Phosphatase 2A regulatory subunit A family
Target Synonyms
2AAB_HUMAN; beta isoform of regulatory subunit A; protein phosphatase 2; PP2A A beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A; subunit A; PR65 beta isoform; PP2A; subunit A; R1 beta isoform; PPP2R1B; PPP4R1; PR65B; protein phosphatase 2 (formerly 2A); regulatory subunit A (PR 65); beta isoform; protein phosphatase 2 (formerly 2A); regulatory subunit A; beta isoform; Protein phosphatase 2; regulatory subunit A; beta; Protein phosphatase 2; structural/regulatory subunit A; beta; protein phosphatase 2; structural/regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A; 65 kDa regulatory subunit A; beta isoform; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Target Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
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