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The antibody against PPP2R2D was raised in rabbit using the Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PPP2R2D was raised in rabbit using the Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human prostate cancer using PPP2R2D Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using PPP2R2D Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using PPP2R2D Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-15373A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP2R2D |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q66LE6 |
Uniprot Id
Q66LE6
Target Species
Human
Target Name
PPP2R2D
Target Full Name
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Target Function
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Phosphatase 2A regulatory subunit B family
Target Synonyms
2ABD_HUMAN; MDS026; PP2A subunit B isoform B55-delta; PP2A subunit B isoform delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; PPP2R2D; Protein phosphatase 2 regulatory subunit B delta; Protein phosphatase 2 regulatory subunit B delta isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
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