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The antibody against PPP2R5D was raised in rabbit using the Synthesized peptide derived from internal of Human PPP2R5D. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against PPP2R5D was raised in rabbit using the Synthesized peptide derived from internal of Human PPP2R5D. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HuvEc cells and Jurkat cells, using PPP2R5D antibody.
| Cat.No | ADC-40924A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP2R5D |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PPP2R5D. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14738 |
Uniprot Id
Q14738
Target Species
Human
Target Name
PPP2R5D
Target Full Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
Target Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Target Involvement
Mental retardation, autosomal dominant 35 (MRD35)
Target Subcellular Location
Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis.
Target Protein Families
Phosphatase 2A regulatory subunit B56 family
Target Tissue Specificity
Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
Target Synonyms
2A5D_HUMAN; B'delta; B56D; Delta isoform of regulatory subunit B56; protein phosphatase 2A; MGC2134; MGC8949; OTTHUMP00000039821; PP2A B subunit B' delta isoform; PP2A B subunit B56 delta isoform; PP2A B subunit isoform B''-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta; PP2A B subunit PR61 delta isoform; PP2A B subunit R5 delta isoform; PPP2R5D; Protein phosphatase 2 regulatory subunit B (B56) delta isoform; Protein phosphatase 2 regulatory subunit B delta isoform; Protein phosphatase 2 regulatory subunit B' delta; Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; TEG-271; Tex271
Target Background
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
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