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Rabbit anti-Human PPT2 Polyclonal Antibody

The antibody against PPT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09272A

The antibody against PPT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09272A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePPT2
Target SynonymsG14; PPT-2; C6orf8; PPT2FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4).Target SpeciesHuman
Uniprot IDQ9UMR5Immunogen Sequence
Background Information
  • Uniprot Id

    Q9UMR5

  • Target Species

    Human

  • Target Name

    PPT2

  • Target Full Name

    Lysosomal thioesterase PPT2

  • Target Function

    Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.

  • Target Subcellular Location

    Lysosome.

  • Target Protein Families

    Palmitoyl-protein thioesterase family

  • Target Tissue Specificity

    Broadly expressed, with highest levels in skeletal muscle.

  • Target Synonyms

    PPT2Lysosomal thioesterase PPT2; PPT-2; EC 3.1.2.-; S-thioesterase G14

  • Target Background

    This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene.

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