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The antibody against PRODH was raised in rabbit using the Recombinant Human Proline dehydrogenase 1, mitochondrial protein (71-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against PRODH was raised in rabbit using the Recombinant Human Proline dehydrogenase 1, mitochondrial protein (71-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-12483A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRODH |
| Target Synonyms | mitochondrial antibody; Proline oxidase, mitochondrial antibody; Proline oxidase 1 antibody; Proline oxidase 2 antibody; Proline oxidase antibody; Proline oxidase, mitochondrial precursor antibody; SCZD4 antibody; TP53I6 antibody; tumor protein p53 inducible protein 6 antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Proline dehydrogenase 1, mitochondrial protein (71-134AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43272 |
Uniprot Id
O43272
Target Species
Human
Target Name
PRODH
Target Full Name
Proline dehydrogenase 1, mitochondrial
Target Function
Converts proline to delta-1-pyrroline-5-carboxylate.
Target Involvement
Hyperprolinemia 1 (HYRPRO1); Schizophrenia 4 (SCZD4)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Proline oxidase family
Target Tissue Specificity
Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas.
Target Synonyms
HSPOX2; mitochondrial; P53 induced gene 6 protein ; p53-induced gene 6 protein; PIG6; POX; PROD_HUMAN; PRODH 1; PRODH 2; PRODH; PRODH1; PRODH2; Proline dehydrogenase ; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase); Proline dehydrogenase 1; Proline dehydrogenase 1, mitochondrial; Proline oxidase 1; Proline oxidase 2; Proline oxidase; Proline oxidase, mitochondrial; Proline oxidase, mitochondrial precursor ; SCZD4; TP53I6; tumor protein p53 inducible protein 6
Target Background
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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