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Rabbit anti-Human PROKR2 Polyclonal Antibody

The antibody against PROKR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human PROKR2 (NP_658986.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04226A

The antibody against PROKR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human PROKR2 (NP_658986.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04226A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePROKR2
Target SynonymsHH3; KAL3; PKR2; GPRg2; GPR73b; GPR73L1; dJ680N4.3; PROKR2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293T, Mouse thymus, SKOV3, U-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human PROKR2 (NP_658986.1).Target SpeciesHuman
Immunogen SequenceMAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALUniprot IDQ8NFJ6
Background Information
  • Uniprot Id

    Q8NFJ6

  • Target Species

    Human

  • Target Name

    PROKR2

  • Target Full Name

    Prokineticin receptor 2

  • Target Function

    Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.

  • Target Involvement

    Hypogonadotropic hypogonadism 3 with or without anosmia (HH3)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain.

  • Target Synonyms

    PROKR2; GPR73L1; PKR2; Prokineticin receptor 2; PK-R2; G-protein coupled receptor 73-like 1; G-protein coupled receptor I5E; GPR73b; GPRg2

  • Target Background

    Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins.

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