Rabbit anti-Human PRPF3 Polyclonal Antibody

The antibody against PRPF3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PRPF3 (NP_004689.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, IP, ELISA.

ADA-09683A

Number

Cat.No	ADA-09683A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PRPF3
Target Synonyms	PRP3; RP18; HPRP3; Prp3p; HPRP3P; SNRNP90; PRPF3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	THP-1	Application	ELISA, WB, IF/ICC, IHC-P, IP

Cat.No

ADA-09683A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PRPF3

Target Synonyms

PRP3; RP18; HPRP3; Prp3p; HPRP3P; SNRNP90; PRPF3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

THP-1

Application

ELISA, WB, IF/ICC, IHC-P, IP

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PRPF3 (NP_004689.1).	Target Species	Human
Uniprot ID	O43395	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PRPF3 (NP_004689.1).

Target Species

Human

Uniprot ID

O43395

Immunogen Sequence

Background Information

Uniprot Id

O43395
Target Species

Human
Target Name

PRPF3
Target Full Name

U4/U6 small nuclear ribonucleoprotein Prp3
Target Function

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Target Involvement

Retinitis pigmentosa 18 (RP18)
Target Subcellular Location

Nucleus. Nucleus speckle.
Target Tissue Specificity

Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain.
Target Synonyms

hPrp3; HPRP3P; Pre mRNA splicing factor 3; Pre-mRNA-splicing factor 3; Precursor mRNA-processing factor 3; S. crevisiae; homolog of; PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae); Prp3p; PRPF3; PRPF3_HUMAN; RP18; SNRNP90; U4/U6 small nuclear ribonucleoprotein PRP3; U4/U6 snRNP 90 kDa protein
Target Background

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

Rabbit anti-Human PRPF3 Polyclonal Antibody

Specifications

Immunogen Information

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