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Rabbit anti-Human PRPF31 Monoclonal Antibody

The antibody against PRPF31 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human PRPF31 (Q8WWY3) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13291A

The antibody against PRPF31 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human PRPF31 (Q8WWY3) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13291A ClonalityMonoclonal
Host SpeciesRabbitTarget NamePRPF31
Target SynonymsRP11; PRP31; SNRNP61; NY-BR-99; PRPF31FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, A-549, JurkatApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 350-450 of human PRPF31 (Q8WWY3).Target SpeciesHuman
Immunogen SequenceQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASUniprot IDQ8WWY3
Background Information
  • Uniprot Id

    Q8WWY3

  • Target Species

    Human

  • Target Name

    PRPF31

  • Target Full Name

    U4/U6 small nuclear ribonucleoprotein Prp31

  • Target Function

    Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.

  • Target Involvement

    Retinitis pigmentosa 11 (RP11)

  • Target Subcellular Location

    Nucleus. Nucleus speckle. Nucleus, Cajal body.

  • Target Protein Families

    PRP31 family

  • Target Tissue Specificity

    Ubiquitously expressed.

  • Target Synonyms

    DKFZp566J153; hPrp 31; hPrp31; NY BR 99; Pre mRNA processing factor 31; Pre mRNA processing factor 31 homolog (yeast); Pre mRNA processing factor 31 homolog; Pre-mRNA-processing factor 31; Precursor mRNA-processing factor 31; S. cerevisiae; homolog of; Protein 61K; PRP 31; PRP31; PRP31 pre mRNA processing factor 31 homolog (yeast); PRP31 pre mRNA processing factor 31 homolog; PRP31_HUMAN; PRPF 31; prpf31; RP 11; RP11; Serologically defined breast cancer antigen NY BR 99; Serologically defined breast cancer antigen NY-BR-99; SNRNP61; U4/U6 small nuclear ribonucleoprotein Prp31; U4/U6 snRNP 61 kDa protein

  • Target Background

    This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

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