Rabbit anti-Human PRPF31 Polyclonal Antibody

The antibody against PRPF31 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRPF31 (NP_056444.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03695A

Number

Cat.No	ADA-03695A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PRPF31
Target Synonyms	RP11; PRP31; SNRNP61; NY-BR-99; PRPF31	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HepG2, Jurkat, Mouse lung, Mouse testis, Rat lung, Rat testis, U-251MG	Application	ELISA, WB, IHC-P

Cat.No

ADA-03695A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PRPF31

Target Synonyms

RP11; PRP31; SNRNP61; NY-BR-99; PRPF31

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HepG2, Jurkat, Mouse lung, Mouse testis, Rat lung, Rat testis, U-251MG

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRPF31 (NP_056444.3).	Target Species	Human
Immunogen Sequence	MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNAS	Uniprot ID	Q8WWY3

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRPF31 (NP_056444.3).

Target Species

Human

Immunogen Sequence

MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNAS

Uniprot ID

Q8WWY3

Background Information

Uniprot Id

Q8WWY3
Target Species

Human
Target Name

PRPF31
Target Full Name

U4/U6 small nuclear ribonucleoprotein Prp31
Target Function

Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
Target Involvement

Retinitis pigmentosa 11 (RP11)
Target Subcellular Location

Nucleus. Nucleus speckle. Nucleus, Cajal body.
Target Protein Families

PRP31 family
Target Tissue Specificity

Ubiquitously expressed.
Target Synonyms

DKFZp566J153; hPrp 31; hPrp31; NY BR 99; Pre mRNA processing factor 31; Pre mRNA processing factor 31 homolog (yeast); Pre mRNA processing factor 31 homolog; Pre-mRNA-processing factor 31; Precursor mRNA-processing factor 31; S. cerevisiae; homolog of; Protein 61K; PRP 31; PRP31; PRP31 pre mRNA processing factor 31 homolog (yeast); PRP31 pre mRNA processing factor 31 homolog; PRP31_HUMAN; PRPF 31; prpf31; RP 11; RP11; Serologically defined breast cancer antigen NY BR 99; Serologically defined breast cancer antigen NY-BR-99; SNRNP61; U4/U6 small nuclear ribonucleoprotein Prp31; U4/U6 snRNP 61 kDa protein
Target Background

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Rabbit anti-Human PRPF31 Polyclonal Antibody

Specifications

Immunogen Information

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