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The antibody against PRRG2 was raised in rabbit using the Human PRRG2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PRRG2 was raised in rabbit using the Human PRRG2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47508A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRRG2 |
| Target Synonyms | PRRG2; PRGP2; TMG2; Transmembrane gamma-carboxyglutamic acid protein 2; Proline-rich gamma-carboxyglutamic acid protein 2; Proline-rich Gla protein 2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PRRG2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14669 |
Uniprot Id
O14669
Target Species
Human
Target Name
PRRG2
Target Full Name
Transmembrane gamma-carboxyglutamic acid protein 2
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Widely expressed with highest levels in kidney. Also highly expressed in the thyroid.
Target Synonyms
PRRG2; PRGP2; TMG2; Transmembrane gamma-carboxyglutamic acid protein 2; Proline-rich gamma-carboxyglutamic acid protein 2; Proline-rich Gla protein 2
Target Background
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
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