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Rabbit anti-Human PSAT1 Polyclonal Antibody

The antibody against PSAT1 was raised in rabbit using the Human PSAT1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-47504A

The antibody against PSAT1 was raised in rabbit using the Human PSAT1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-47504A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePSAT1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PSAT1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y617
Background Information
  • Uniprot Id

    Q9Y617

  • Target Species

    Human

  • Target Name

    PSAT1

  • Target Full Name

    Phosphoserine aminotransferase

  • Target Function

    Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

  • Target Involvement

    Phosphoserine aminotransferase deficiency (PSATD); Neu-Laxova syndrome 2 (NLS2)

  • Target Protein Families

    Class-V pyridoxal-phosphate-dependent aminotransferase family, SerC subfamily

  • Target Tissue Specificity

    Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.

  • Target Synonyms

    PSA; EPIP; NLS2; PSAT; PSATD; PSAT1

  • Target Background

    This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8.

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