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The antibody against PSMA8 was raised in rabbit using the Human PSMA8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PSMA8 was raised in rabbit using the Human PSMA8 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52212A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSMA8 |
| Target Synonyms | PSMA8 antibody; PSMA7L antibody; Proteasome subunit alpha-type 8 antibody; EC 3.4.25.1 antibody; Proteasome alpha 4 subunit antibody; Alpha4s antibody; Proteasome subunit alpha-type 7-like antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PSMA8 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TAA3 |
Uniprot Id
Q8TAA3
Target Species
Human
Target Name
PSMA8
Target Full Name
Proteasome subunit alpha-type 8
Target Function
Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
Target Subcellular Location
Nucleus.
Target Protein Families
Peptidase T1A family
Target Synonyms
PSMA8; PSMA7L; Proteasome subunit alpha-type 8; EC 3.4.25.1; Proteasome alpha 4 subunit; Alpha4s; Proteasome subunit alpha-type 7-like
Target Background
Predicted to be involved in meiotic cell cycle and proteasomal protein catabolic process. Located in extracellular exosome and nucleus.
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