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The antibody against PSMD6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-307 of human PSMD6 (NP_055629.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PSMD6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-307 of human PSMD6 (NP_055629.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00421A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSMD6 |
| Target Synonyms | S10; Rpn7; p42A; p44S10; SGA-113M; PSMD6 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 23-307 of human PSMD6 (NP_055629.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15008 | Immunogen Sequence |
Uniprot Id
Q15008
Target Species
Human
Target Name
PSMD6
Target Full Name
26S proteasome non-ATPase regulatory subunit 6
Target Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Target Protein Families
Proteasome subunit S10 family
Target Synonyms
26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; KIAA0107; p42A; P44S10; PFAAP4; Phosphonoformate immuno-associated protein 4; Proteasome (prosome; macropain) 26S subunit; non-ATPase; 6; Proteasome regulatory particle subunit p44S10; PSMD6; PSMD6_HUMAN; Rpn7; S10; SGA-113M
Target Background
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants
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