Rabbit anti-Human PSMD6 Polyclonal Antibody

Uniprot Id

Q15008

Target Species

Human

Target Name

PSMD6

Target Full Name

26S proteasome non-ATPase regulatory subunit 6

Target Function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Target Protein Families

Proteasome subunit S10 family

Target Synonyms

26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; KIAA0107; p42A; P44S10; PFAAP4; Phosphonoformate immuno-associated protein 4; Proteasome (prosome; macropain) 26S subunit; non-ATPase; 6; Proteasome regulatory particle subunit p44S10; PSMD6; PSMD6_HUMAN; Rpn7; S10; SGA-113M

Target Background

This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants