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The antibody against PTH1R was raised in rabbit using the Recombinant Human Parathyroid hormone/parathyroid hormone-related peptide receptor protein (485-593AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against PTH1R was raised in rabbit using the Recombinant Human Parathyroid hormone/parathyroid hormone-related peptide receptor protein (485-593AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-08410A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTH1R |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Parathyroid hormone/parathyroid hormone-related peptide receptor protein (485-593AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03431 |
Uniprot Id
Q03431
Target Species
Human
Target Name
PTH1R
Target Full Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
Target Function
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Target Involvement
Jansen metaphyseal chondrodysplasia (JMC); Chondrodysplasia Blomstrand type (BOCD); Enchondromatosis multiple (ENCHOM); Eiken skeletal dysplasia (EISD); Primary failure of tooth eruption (PFE)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Expressed in most tissues. Most abundant in kidney, bone and liver.
Target Synonyms
PFE; EKNS; PTHR; PTHR1; PTH1R
Target Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
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