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Rabbit anti-Human PTH2R Polyclonal Antibody

The antibody against PTH2R was raised in rabbit using the Recombinant Human Parathyroid hormone 2 receptor protein (27-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-49933A

The antibody against PTH2R was raised in rabbit using the Recombinant Human Parathyroid hormone 2 receptor protein (27-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-49933A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePTH2R
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Parathyroid hormone 2 receptor protein (27-145AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49190
Background Information
  • Uniprot Id

    P49190

  • Target Species

    Human

  • Target Name

    PTH2R

  • Target Full Name

    Parathyroid hormone 2 receptor

  • Target Function

    This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 2 family

  • Target Tissue Specificity

    Expressed abundantly in brain and pancreas. Also expressed in the testis.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor ; PTH 2 receptor ; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2

  • Target Background

    The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.

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