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The antibody against PTH2R was raised in rabbit using the Recombinant Human Parathyroid hormone 2 receptor protein (27-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against PTH2R was raised in rabbit using the Recombinant Human Parathyroid hormone 2 receptor protein (27-145AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-49933A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTH2R |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Parathyroid hormone 2 receptor protein (27-145AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49190 |
Uniprot Id
P49190
Target Species
Human
Target Name
PTH2R
Target Full Name
Parathyroid hormone 2 receptor
Target Function
This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Expressed abundantly in brain and pancreas. Also expressed in the testis.
Target Research Area
Neuroscience
Target Synonyms
Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor ; PTH 2 receptor ; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2
Target Background
The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.
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