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Rabbit anti-Human PTOV1 Polyclonal Antibody

The antibody against PTOV1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTOV1 (NP_001292037.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04622A

The antibody against PTOV1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTOV1 (NP_001292037.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04622A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePTOV1
Target SynonymsACID2; PTOV-1; PTOV1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHT-29ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTOV1 (NP_001292037.1).Target SpeciesHuman
Immunogen SequenceMRSPAVPTPARGQLGVAFVLLPPHSEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLEUniprot IDQ86YD1
Background Information
  • Uniprot Id

    Q86YD1

  • Target Species

    Human

  • Target Name

    PTOV1

  • Target Full Name

    Prostate tumor-overexpressed gene 1 protein

  • Target Function

    May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region.

  • Target Protein Families

    Mediator complex subunit 25 family, PTOV1 subfamily

  • Target Tissue Specificity

    Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.

  • Target Synonyms

    PTOV1; ACID2; PP642; UNQ6127/PRO20092; Prostate tumor-overexpressed gene 1 protein; PTOV-1; Activator interaction domain-containing protein 2

  • Target Background

    This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.

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