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The antibody against PTOV1 was raised in rabbit using the Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PTOV1 was raised in rabbit using the Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04809A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTOV1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86YD1 |
Uniprot Id
Q86YD1
Target Species
Human
Target Name
PTOV1
Target Full Name
Prostate tumor-overexpressed gene 1 protein
Target Function
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
Target Subcellular Location
Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region.
Target Protein Families
Mediator complex subunit 25 family, PTOV1 subfamily
Target Tissue Specificity
Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.
Target Synonyms
PTOV1; ACID2; PP642; UNQ6127/PRO20092; Prostate tumor-overexpressed gene 1 protein; PTOV-1; Activator interaction domain-containing protein 2
Target Background
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.
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