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The antibody against PTPRU was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PTPRU was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01299A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTPRU |
| Target Synonyms | FMI; PTP; PCP-2; PTP-J; PTPRO; PTPU2; PTP-PI; PTP-RO; PTPPSI; hPTP-J; R-PTP-U; R-PTP-PSI; PTPRU | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCV | Uniprot ID | Q92729 |
Uniprot Id
Q92729
Target Species
Human
Target Name
PTPRU
Target Full Name
Receptor-type tyrosine-protein phosphatase U
Target Function
Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis.
Target Subcellular Location
Cell junction. Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Protein-tyrosine phosphatase family, Receptor class 2B subfamily
Target Tissue Specificity
High levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; not expressed in placenta and spleen. Also detected in heart, prostate, lung, thymus, testis and ovary. Ubiquitously expressed in brain. Expressed by h
Target Synonyms
PTPRU; FMI; PCP2; PTPRO; Receptor-type tyrosine-protein phosphatase U; R-PTP-U; EC 3.1.3.48; Pancreatic carcinoma phosphatase 2; PCP-2; Protein-tyrosine phosphatase J; PTP-J; hPTP-J; Protein-tyrosine phosphatase pi; PTP pi; Protein-tyrosine phosphatase receptor omicron; PTP-RO; Receptor-type protein-tyrosine phosphatase psi; R-PTP-psi
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