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The antibody against PTX3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 18-381 of human PTX3 (NP_002843.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PTX3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 18-381 of human PTX3 (NP_002843.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11810A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTX3 |
| Target Synonyms | TSG-14; TNFAIP5; PTX3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | NIH/3T3, Rat brain, A375, HepG2, HL-60, Jurkat, Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 18-381 of human PTX3 (NP_002843.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P26022 | Immunogen Sequence |
Uniprot Id
P26022
Target Species
Human
Target Name
PTX3
Target Full Name
Pentraxin-related protein PTX3
Target Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Target Subcellular Location
Secreted.
Target Synonyms
AI607804; Pentaxin 3; Pentaxin-related protein PTX3; Pentraxin 3 long; Pentraxin-related gene; Pentraxin-related gene rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3_HUMAN; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14
Target Background
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
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