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The antibody against PYCR2 was raised in rabbit using the Human PYCR2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PYCR2 was raised in rabbit using the Human PYCR2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47457A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PYCR2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., 0.02% Sodium Azide, 0.1M Glycine, 0.1M NaHCO3 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human PYCR2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96C36 |
Uniprot Id
Q96C36
Target Species
Human
Target Name
PYCR2
Target Full Name
Pyrroline-5-carboxylate reductase 2
Target Function
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress.
Target Involvement
Leukodystrophy, hypomyelinating, 10 (HLD10)
Target Subcellular Location
Cytoplasm. Mitochondrion.
Target Protein Families
Pyrroline-5-carboxylate reductase family
Target Tissue Specificity
Detected in erythrocytes (at protein level). Expressed in fetal brain.
Target Synonyms
1810018M05Rik; FLJ54750; Leftb; OTTHUMP00000035614; P5C reductase 2; P5CR 2; P5CR2; P5CR2_HUMAN; PYCR 2; PYCR2; Pyrroline 5 carboxylate reductase 2; Pyrroline 5 carboxylate reductase family member 2; Pyrroline 5 carboxylate reductase isoform; Pyrroline-5-carboxylate reductase 2; RP4-559A3.4
Target Background
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene.
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