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The antibody against PZP was raised in rabbit using the Human PZP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PZP was raised in rabbit using the Human PZP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47455A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PZP |
| Target Synonyms | PZP antibody; CPAMD6 antibody; Pregnancy zone protein antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PZP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20742 |
Uniprot Id
P20742
Target Species
Human
Target Name
PZP
Target Full Name
Pregnancy zone protein
Target Function
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Target Subcellular Location
Secreted.
Target Protein Families
Protease inhibitor I39 (alpha-2-macroglobulin) family
Target Tissue Specificity
Plasma. Prominent constituent of late-pregnancy sera.
Target Research Area
Neuroscience
Target Synonyms
PZP; CPAMD6; Pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
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