Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against QPRT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against QPRT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05703A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | QPRT |
| Target Synonyms | QPRTase; HEL-S-90n; QPRT | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15274 | Immunogen Sequence |
Uniprot Id
Q15274
Target Species
Human
Target Name
QPRT
Target Full Name
Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Target Function
Involved in the catabolism of quinolinic acid (QA).
Target Protein Families
NadC/ModD family
Target Synonyms
NADC_HUMAN; Nicotinate nucleotide pyrophosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]; Quinolinate phosphoribosyltransferase
Target Background
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
