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The antibody against QRSL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 289-528 of human QRSL1 (NP_060762.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against QRSL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 289-528 of human QRSL1 (NP_060762.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01245A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | QRSL1 |
| Target Synonyms | GatA; COXPD40; QRSL1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 289-528 of human QRSL1 (NP_060762.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H0R6 | Immunogen Sequence |
Uniprot Id
Q9H0R6
Target Species
Human
Target Name
QRSL1
Target Full Name
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
Target Function
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Target Involvement
Defects in QRSL1 may play a role in mitochondrial disorders characterized by combined respiratory chain complex deficiencies.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Amidase family, GatA subfamily
Target Synonyms
QRSL1; Glutamyl-tRNA(Gln) amidotransferase subunit A; mitochondrial; Glu-AdT subunit A; EC 6.3.5.7; Glutaminyl-tRNA synthase-like protein 1
Target Background
Enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA(Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 40.
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