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The antibody against RAB18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human RAB18 (NP_067075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RAB18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human RAB18 (NP_067075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11273A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAB18 |
| Target Synonyms | WARBM3; RAB18LI1; RAB18 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 293T, A375, MCF7, Mouse liver, Rat liver, SH-SY5Y | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human RAB18 (NP_067075.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NP72 | Immunogen Sequence |
Uniprot Id
Q9NP72
Target Species
Human
Target Name
RAB18
Target Full Name
Ras-related protein Rab-18
Target Function
Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts. Plays a role in apical endocytosis/recycling. Plays a key role in eye and brain development and neurodegeneration.
Target Involvement
Warburg micro syndrome 3 (WARBM3)
Target Subcellular Location
Apical cell membrane. Lipid droplet.
Target Protein Families
Small GTPase superfamily, Rab family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Signal Transduction
Target Synonyms
AA959686; RAB18; RAB18 small GTPase; RAB18; member RAS oncogene family; RAB18_HUMAN; RAB18LI1; Ras related protein Rab 18; Ras-asssociated protein RAB18; Ras-related protein Rab-18; RP11-148B2.1; WARBM3
Target Background
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.
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