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Rabbit anti-Human RAD54B Polyclonal Antibody

The antibody against RAD54B was raised in rabbit using the Recombinant Human DNA repair and recombination protein RAD54B protein (1-167AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-14128A

The antibody against RAD54B was raised in rabbit using the Recombinant Human DNA repair and recombination protein RAD54B protein (1-167AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-14128A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRAD54B
Target SynonymsRAD54B antibody; DNA repair and recombination protein RAD54B antibody; EC 3.6.4.- antibody; RAD54 homolog B antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human DNA repair and recombination protein RAD54B protein (1-167AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y620
Background Information
  • Uniprot Id

    Q9Y620

  • Target Species

    Human

  • Target Name

    RAD54B

  • Target Full Name

    DNA repair and recombination protein RAD54B

  • Target Function

    Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SNF2/RAD54 helicase family

  • Target Tissue Specificity

    Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.

  • Target Synonyms

    RAD54B; DNA repair and recombination protein RAD54B; EC 3.6.4.-; RAD54 homolog B

  • Target Background

    The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

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