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The antibody against RAI1 was raised in rabbit using the Recombinant Human Retinoic acid-induced protein 1 protein (617-823AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against RAI1 was raised in rabbit using the Recombinant Human Retinoic acid-induced protein 1 protein (617-823AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human heart tissue using RAI1 Antibody at dilution of 1:1002
| Cat.No | ADC-10328A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAI1 |
| Target Synonyms | RAI1 antibody; KIAA1820 antibody; Retinoic acid-induced protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Retinoic acid-induced protein 1 protein (617-823AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z5J4 |
Uniprot Id
Q7Z5J4
Target Species
Human
Target Name
RAI1
Target Full Name
Retinoic acid-induced protein 1
Target Function
Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation.
Target Involvement
Smith-Magenis syndrome (SMS)
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Expressed in all tissues examined with higher expression in the heart and brain. No expression was seen in the corpus callosum of the brain.
Target Synonyms
RAI1; KIAA1820; Retinoic acid-induced protein 1
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