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The antibody against RALY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 96-306 of human RALY (NP_057951.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RALY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 96-306 of human RALY (NP_057951.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02061A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RALY |
| Target Synonyms | P542; HNRPCL2; RALY | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, Mouse lung, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 96-306 of human RALY (NP_057951.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UKM9 | Immunogen Sequence |
Uniprot Id
Q9UKM9
Target Species
Human
Target Name
RALY
Target Full Name
RNA-binding protein Raly
Target Function
RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
Target Subcellular Location
Nucleus.
Target Protein Families
RRM HNRPC family, RALY subfamily
Target Tissue Specificity
Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
Target Synonyms
Autoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP associated with lethal yellow protein homolog; hnRNP core protein C-like 2; MGC117312; P542; RALY; RALY_HUMAN; RNA binding protein (autoantigenic hnRNP associated with lethal yellow); RNA binding protein (autoantigenic); RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)); RNA-binding protein Raly
Target Background
This gene encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) gene family. This protein may play a role in pre-mRNA splicing and in embryonic development. Alternate splicing results in multiple transcript variants.
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